Photocytotoxicity studies of polyamidoamine (PAMAM) dendrimer and its glucoheptoamidated derivative as delivery drug systems in local PUVA photochemotherapy
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چکیده
منابع مشابه
CMC/PAMAM Dendrimer Nanoparticles as Intracellular Drug Delivery Systems for Spinal Cord Injury Applications
Galway, Ireland CMC/PAMAM Dendrimer Nanoparticles as Intracellular Drug Delivery Systems for Spinal Cord Injury Applications Susana R. Cerqueira, V.H. Pereira, Joaquim M. Oliveira, João F. Mano, Nuno Sousa, António J. Salgado, Rui L. Reis 2,3 Corresponding Author: [email protected] 3B's Research Group Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters o...
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هدف از این مطالعه بررسی امکان استفاده از داروهای شناخته شده در درمان سایر بیماریها به عنوان داروهای ضد سرطان است. همچنین با استفاده از این داروها در ساختمان کمپلکس فلز می توان شاخص های دارویی بدست آمده را بررسی نمود. داروی ضد ویروس ایدز(hiv)به نام زیدوودین(azt)انتخاب و.کمپلکس.محلول.در.آب[pt(azt)2]cl2سنتزو به روشهای مختلف فیزیکی و شیمیایی شناسایی گردید. بر هم کنش مقایسه ای این دارو و کمپلکس پلا...
15 صفحه اولStructural studies of biologically active glycosylated polyamidoamine (PAMAM) dendrimers.
The partial modification of carboxylic acid terminated polyamidoamine (PAMAM) dendrimers with glucosamine has been reported to give dendrimer glucosamine conjugates novel immuno-modulatory and anti-angiogenic properties. Experimental analysis of these glycosylated dendrimers showed that, on average, eight glucosamine molecules were covalently bound to each dendrimer. In order to better understa...
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The use of tumor-specific therapeutic agents is a promising option for efficient and safe nonviral gene transfer in gene therapy. In this study, we describe the efficacy of polyamidoamine (PAMAM)-based nonviral gene delivery carriers, namely, an ornithine conjugated PAMAM (PAMAM-O) dendrimer in delivering apoptin, a tumor-specific killer gene, into human hepatocellular carcinoma (HepG2 cells) a...
متن کاملPhototherapy and PUVA photochemotherapy in children.
The use of phototherapy and photochemotherapy in children has been limited due to concerns over their long-term carcinogenic potential. Furthermore, the method of administration is disconcerting to some children, particularly as phototherapy treatment units are seldom rendered 'child-friendly'. Despite these reservations, ultra-violet therapies can be useful treatment options for children with ...
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ژورنال
عنوان ژورنال: Our Dermatology Online
سال: 2017
ISSN: 2081-9390
DOI: 10.7241/ourd.2017e.12